CD36 (Platelet & Microvessel Marker) MBS439727 from MyBioSource.com

Product Specs
ItemCD36 (Platelet & Microvessel Marker)
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS439727
Quantity0.1 mg
ApplicationsFunctional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF)
ConcentrationPurified Ab with BSA and Azide at 200ug/ml
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ReactivityHuman
TargetCD36
IsotypeIgG2a kappa
Molecular WeightAntigen: 80-90kDa
Clone185-1G2
HostMouse
ImmunogenRecognizes a protein of 80kDa-90kDa, identified as CD36. Its epitope maps between aa155-183. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. This MAb blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation
NCBI Full Gene NameCD36 molecule (thrombospondin receptor)
NCBI Gene AliasesCHDS7, GPIV, SCARB3, FAT, PASIV, GP3B, BDPLT10, GP4
ClonalityMonoclonal